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Healthy inflammatory response, Tissue rejuvenation, Cellular debris clearance
Adults with low weekly fish intake or those seeking daily support for post-exercise recovery and active lifestyles.
Take 1 softgel once daily, preferably with a meal to enhance comfort and absorption of the oil-based nutrients.
Gluten-Free; Non-GMO LE-certified; Contains: Fish (squid, anchovy, sardine, herring, mackerel)
18-HEPE is an omega-3–derived intermediate that the body converts into specialised pro-resolving mediators that help switch off inflammatory signalling and assist clearance of cellular debris.
Caution: Sourced from fish; avoid if you have a fish allergy or follow strict avoidance of marine products.
17-HDHA is a DHA-derived precursor that can be converted into resolving compounds involved in ending inflammatory cascades and promoting tissue restoration.
Caution: Fish-derived; those with fish allergies or sensitivities should avoid or choose an alternative source.
14-HDHA acts as a DHA-derived pathway intermediate that may signal resolution processes and support orderly clean-up of cellular by-products.
Caution: Fish-derived; discontinue if unusual reactions occur and consider alternatives if allergic to fish.
These omega-3–derived intermediates feed into the body’s resolution pathways, where 18-HEPE from EPA and 17-HDHA and 14-HDHA from DHA are converted into distinct families of resolving compounds. Together they provide complementary inputs that help the body wind down inflammatory signalling and organise debris clearance.
Label Warning: Do not exceed the recommended dose. Do not use if the outer seal is damaged. Consult a doctor if you are being treated for a medical condition or if you are pregnant or breastfeeding.
Who should be cautious: People with fish or marine oil sensitivities may wish to exercise caution due to squid, anchovy, sardine, herring, and mackerel sources. Those with bleeding concerns or on blood-thinning medication may wish to discuss marine oil supplements with a healthcare professional before use.
Storage: Store tightly closed in a cool, dry place.
This product is guaranteed authentic and backed by our easy returns and refunds policy. Details
Vitamin D3 and K2 may enhance calcium absorption and utilization, complementing multiminerals for bone health and supporting cardiovascular wellness.
AI generated. Not medical advice.
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What Are Pro-Resolving Mediators?
The body creates specialised pro-resolving mediators (PRMs) from fatty acids such as EPA and DHA omega-3s. It then uses those pro-resolving mediators to promote a healthy post-inflammatory response, supporting healthy tissue rejuvenation and maintaining the vital balance between cytokine compounds. This formula combines PRMs and PRM precursors.
The body uses pro-resolving mediators to support healthy tissue rejuvenation and to “clean up” cellular debris.
Pro-Resolving Mediators Benefits
In the body, pro-resolving mediators:
Read the entire label and follow the directions carefully before use.
Take one (1) softgel daily, or as advised by a healthcare professional.
Highly refined marine oil concentrate (squid, anchovy, sardine, herring, mackerel), gelatin, olive oil, glycerin, purified water, lemon flavour, mixed tocopherols.
Store tightly closed in a cool, dry place.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally be despatched with alternative packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and do not rely solely on the information provided by iHerb. This website has been machine translated as a courtesy to customers. iHerb does not represent or warrant that the translations are complete or error-free and iHerb is not responsible for any translation errors or omissions.
| Supplement information | ||
| Serving Size: one capsule | ||
| Amount per serving | %Reference Intake | |
| Calories | 5 | |
| Total fat | 0.5 g | 1%† |
| Cholesterol | <5 mg | <2% |
| Marine Lipid Concentrate [providing 300 mcg of Pro-Resolving Mediators including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxydocosahexaenoic acid (17-HDHA), & 14-hydroxydocosahexaenoic acid (14-HDHA)]. | 500 mg | ** |
| **Reference intake not established. †% Reference intakes are based on a 2,000 calorie diet. | ||
